6 p.m. update
Police have opened one westbound lane but traffic is still moving slowly and motorists are advised to use caution.
5:29 p.m. update
Police report one westbound lane has been reopened to traffic but eastbound lanes remain closed. Motorists are advised to use alternate routes.
Motorists can avoid the area of the collision by travelling via Dacey Rd., Queen St. and Fournier Rd.
Original story: 2:28 p.m.
Paramedics, firefighters and city police are at the scene of a serious collision on Trunk Road beside the roadway leading into White Pines Collegiate and Vocational School.
Firefighters have had to extricate two passengers from a black pickup truck. The extent of the injuries is unknown at this time, say police.
The crash, which happened just before 2 p.m., also involved a transport truck, which crashed into a utility pole and a telephone pole. PUC crews are on scene as well.
Police and fire crews have instructed onlookers to stand well back.
Traffic is closed in both directions on Trunk Road as of 2:20 p.m., however a detour is available using Fournier and Dacey Road.
Sault Police Const. Sonny Spina said there may have been other vehicles indirectly involved. The collision is under investigation.