Four fire trucks and a Fire Command Unit are on the scene at Quattro Hotel.
Several people have been evacuated. The entrance of the conference centre and the entrance of Quattro Vinotecca have been taped off.
Traffic in front of the hotel has been reduced to one lane on Great Northern Road heading southbound.
There is currently no smoke or flames in the area.
The cause of the incident is unknown at this time.
SooToday will provide an update when more information becomes available.